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Table 1 Effects of indomethacin plus vitamin E on total brain cortex levels of PGE2, TxB2 and IL-1β in Tg2576 mice. Mice were treated starting at 8-months of age until they were 15-month-old (n = 10 animals per group).

From: Brain inflammation and oxidative stress in a transgenic mouse model of Alzheimer-like brain amyloidosis

  Placebo Indomethacin Vitamin E P
PGE2 (pg/mg tissue) 92 ± 8 39 ± 5* <0.01
TxB2 (pg/mg tissue) 148 ± 10 15 ± 4* <0.001
IL-1β (pg/mg protein) 75 ± 12 33 ± 8* <0.01
  1. Values are expressed as means ± S.E.M.