Figure 3

Aβ downregulates expression of the oxLDL receptor CD36. A. Analysis of CD36 and SRA mRNA in peritoneal macrophages treated with Aβ (20 μM) by quantitative RT-PCR. Data represent the mean of triplicate samples ± standard deviation, *p ≤ 0.005. B. Western blot analysis confirming CD36 protein downregulation by Aβ. The signal was recorded and the integrated density value quantified using an Alpha Innotech FluorChem Imager and normalized to actin protein. Data are representative of 2 experiments.