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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Ginkgolide B inhibits the neurotoxicity of prions or amyloid-β1-42

Figure 4

Ginkgolides protect sPrP106 or amyloid-β damaged neurons against microglia. Primary cortical neurons were pre-treated with control medium (Con), with 1 μM ginkgolide A, with 1 μM ginkgolide B, with 25 μM quercetin (Quer) or with 25 μM myrecetin (Myr) for 3 hours were then incubated with 5 μM sPrP106 (open squares) or 10 μM amyloid-β1-42 (shaded bars). Neuronal survival was determined 4 days later after the removal of microglia using the WST-1 assay. Values shown represent the percentage survival of treated cells compared to untreated cells. Each point represents the mean ± SD from triplicate experiments repeated 4 times (12 observations).

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