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Table 1 Demographic and clinical characteristics of the study subjects

From: Toll-like receptor 9 promoter polymorphism is associated with decreased risk of Alzheimer’s disease in Han Chinese

  AD (n = 1,133) Control (n = 1,159) P-value
Age at examination (years) (mean ± SD) 79.94 ± 8.12 74.48 ± 6.29  
Age at onset (years) (mean ± SD) 75.01 ± 8.00   0.078a
Gender, n (%)    
Male 464 (41.0) 518 (44.7) 0.070
Female 669 (59.0) 641 (55.3)  
MMSE (mean ± SD) 10.06 ± 3.82 28.26 ± 1.08 < 0.001
ApoE ϵ4 status, n (%)    
ApoE ϵ4 carrier 315 (27.8) 158 (13.6) < 0.001
ApoE ϵ4 noncarrier 818 (72.2) 1,001 (86.4)  
  1. a P value was calculated with the age of onset for late-onset AD and age at examination for controls. AD, Alzheimer’s disease; ApoE ϵ4, apolipoprotein E ϵ4; MMSE, Mini-Mental State Examination.