Table 3 Genotype and allele frequencies for rs187084 stratified by apolipoprotein E ϵ4 (ApoE) status
rs187084 | n | Genotype | P | Allele | P | OR (95% CI) | |||
|---|---|---|---|---|---|---|---|---|---|
GG (%) | GA (%) | AA (%) | G (%) | A (%) | |||||
AD | 1,133 | 150 (13.2) | 557 (49.2) | 426 (37.6) | 0.100 | 857 (37.8) | 1,409 (62.6) | 0.076 | 0.898 (0.798 to 1.011) |
Control | 1,159 | 190 (16.4) | 556 (48.0) | 413 (35.6) | 936 (40.4) | 1,382 (59.6) | |||
ApoE ϵ4 carriers | |||||||||
AD | 315 | 30 (9.5) | 156 (49.5) | 129 (40.1) | < 0.001 | 216 (34.3) | 414 (65.7) | 0.003 | 0.656 (0.498 to 0.865) |
Control | 158 | 38 (24.1) | 64 (40.5) | 56 (35.4) | 140 (44.3) | 176 (55.7) | |||
ApoE ϵ4 noncarriers | |||||||||
AD | 818 | 120 (14.7) | 401(49.0) | 297 (36.3) | 0.936 | 641 (39.2) | 995 (60.8) | 0.722 | 0.976 (0.854 to 1.116) |
Control | 1,001 | 152 (15.2) | 492 (49.2) | 357 (35.7) | 796 (39.8) | 1,206 (60.2) | |||