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Table 3 Genotype and allele frequencies for rs187084 stratified by apolipoprotein E ϵ4 (ApoE) status

From: Toll-like receptor 9 promoter polymorphism is associated with decreased risk of Alzheimer’s disease in Han Chinese

rs187084 n Genotype P Allele P OR (95% CI)
   GG (%) GA (%) AA (%)   G (%) A (%)   
AD 1,133 150 (13.2) 557 (49.2) 426 (37.6) 0.100 857 (37.8) 1,409 (62.6) 0.076 0.898 (0.798 to 1.011)
Control 1,159 190 (16.4) 556 (48.0) 413 (35.6)   936 (40.4) 1,382 (59.6)   
ApoE ϵ4 carriers
AD 315 30 (9.5) 156 (49.5) 129 (40.1) < 0.001 216 (34.3) 414 (65.7) 0.003 0.656 (0.498 to 0.865)
Control 158 38 (24.1) 64 (40.5) 56 (35.4)   140 (44.3) 176 (55.7)   
ApoE ϵ4 noncarriers
AD 818 120 (14.7) 401(49.0) 297 (36.3) 0.936 641 (39.2) 995 (60.8) 0.722 0.976 (0.854 to 1.116)
Control 1,001 152 (15.2) 492 (49.2) 357 (35.7)   796 (39.8) 1,206 (60.2)   
  1. AD, Alzheimer’s disease; ApoE ϵ4, apolipoprotein E ϵ4; CI, confidence interval; OR, odds ratio.