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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Anti-inflammatory and immunomodulatory mechanisms of mesenchymal stem cell transplantation in experimental traumatic brain injury

Figure 2

Modified neurologic severity score (mNSS) and brain water content. (A) Neurological function was analyzed by mNSS on days 1, 3, 7, 14, 21 and 28 after TBI. Treatment with MSCs significantly lowered mNSS from days 3–28 compared with the PBS group. There was no significant difference in scores between the MSC- and PBS-treated groups only at 24 h post-TBI (n = 6 per group). (B) Brain water content of ipsilateral hemispheres was measured at 72 h after injury. The PBS group had a significantly higher brain water content than the sham-injured control group. MSC treatment significantly reduced brain water content compared with the PBS group (n = 6 per group). Data are presented as the mean ± SD. *p < 0.05, **p < 0.01.

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Journal of Neuroinflammation

ISSN: 1742-2094