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Table 2 Spleen cell yield from sham and MCAO-subjected WT, PD-L1 -/- , and PD-L2 -/- mice

From: PD-L1 enhances CNS inflammation and infarct volume following experimental stroke in mice in opposition to PD-1

A

B

Cell yield (× 106)

Cell yield (× 106)

WT

PD-L1 -/-

PD-L2 -/-

WT

PD-L1 -/-

PD-L2 -/-

Sham (n)

Sham (n)

Sham (n)

MCAO (n)

MCAO (n)

MCAO (n)

79.9 ± 4.5 (9)

85.6 ± 3.1 (13)

94.3 ± 3.6 (10)

8.9 ± 7.3 (12)a,b

23.1 ± 3.5 (19)a

19.5 ± 1.9 (14)a

  1. Data are presented as mean ± SEM. aValue of P ≤0.05 with respect to the strain’s sham group; bvalue of P ≤0.05 versus MCAO-induced PD-L1-/- mice. -/-, knockout; MCAO, middle cerebral artery occlusion; PD-L1, programmed death-1 ligand 1; PD-L2, programmed death-1 ligand 2; WT, wild-type.