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Table 4 Percentage of dead (propidium iodide (PI + )) cells in spleens of WT, PD-L1 -/- , and PD-L2 -/- male mice 96 hours after MCAO

From: PD-L1 enhances CNS inflammation and infarct volume following experimental stroke in mice in opposition to PD-1

Dead cells (PI+%)

WT

PD-L1-/-

PD-L2-/-

MCAO (n)

MCAO (n)

MCAO (n)

24.3 ± 6.4 (12)a

18.3 ± 2.4 (19)

20.2 ± 3.9 (14)

  1. Data are presented as mean ± SEM. aValue of P ≤0.05 versus MCAO-induced PD-L1-/- mice. -/-, knockout; MCAO, middle cerebral artery occlusion; PD-L1, programmed death-1 ligand 1; PD-L2, programmed death-1 ligand 2; PI, propidium iodide; WT, wild-type.
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Journal of Neuroinflammation

ISSN: 1742-2094