Figure 4
From: Exercise reduces activation of microglia isolated from hippocampus and brain of aged mice
Proportion of hippocampal microglia positive for MHC II and CD86, Experiment 2. (A) Percentage of hippocampal microglia isolated from running-wheel (n=7) and control (n=7) aged females from Experiment 2 that were positive for MHC II. Wheel-running significantly decreased the proportion of MHC II positive microglia in the hippocampus. (B) Percentage of hippocampal microglia isolated from running-wheel and control aged females that were positive for CD86. The proportion of CD86 positive microglia was significantly reduced by running-wheel access. Means ± SEM. * indicates a significant difference from control mice.