Leukocyte infiltration in experimental stroke

Table 2 Amount of neutrophils (normalized) at different time points post-ischemia listed according to duration of occlusion (tMCAO and pMCAO)

Occlusion time	Amount of neutrophils (survival time)										Strain	n	Marker	Reference
	4 hours	6 hours	12 hours	18 hours	1 day	2 days	3 days	4 days	5 days	7 days
30 minutes					-	++		+++		+++	C57Bl/6	4	Anti-neutro	[31]
30 minutes					-	+		+++		+	C57Bl/6	4	Anti-neutro	[32]
60 minutes	+				+	++	+++				C57Bl/6	6	NIMP-R14	[25]
60 minutes	-				++		+++				C57Bl/6	5	PMN	[33]
60 minutes				-	+	++	+++	++			C57Bl/6 J	7	Lγ-6G	[34]
60 minutes						+++	++		+	-	Wistar	4	MPO	[35]
60 minutes		-	++		++		+++			-	Wistar	6	MPO	[36]
120 minutes			++		+++		+				Wistar	8	MPO	[37]
120 minutes					+++			-		-	Sprague–Dawley	5	H&E	[38]
120 minutes^Δ		+	++		+++	+++	+	-		-	Wistar	4	H&E	[28]
pMCAO^Δ			-		+	+	+++	+		-	Wistar	6	H&E	[26]
pMCAO^Δ		-	-		+	+++	++	-		-	Wistar	5	H&E	[28]

Crosses represent the following amount of cells presented as percentage of the highest cell number: +, 25 to 49%; ++, 50 to 94%; +++, 95 to 100%; -, <25%. ^ΔWeighted average. H&E, hematoxylin and eosin; MPO, myeloperoxidase; n, number of animals included; neutro, neutrophil granulocyte; pMCAO, permanent middle cerebral artery occlusion; PMN, polymorphonuclear; tMCAO, transient middle cerebral artery occlusion.

ISSN: 1742-2094