Skip to main content

Table 2 Amount of neutrophils (normalized) at different time points post-ischemia listed according to duration of occlusion (tMCAO and pMCAO)

From: Leukocyte infiltration in experimental stroke

Occlusion time Amount of neutrophils (survival time) Strain n Marker Reference
  4 hours 6 hours 12 hours 18 hours 1 day 2 days 3 days 4 days 5 days 7 days     
30 minutes      - ++   +++   +++ C57Bl/6 4 Anti-neutro [31]
30 minutes      - +   +++   + C57Bl/6 4 Anti-neutro [32]
60 minutes +     + ++ +++     C57Bl/6 6 NIMP-R14 [25]
60 minutes -     ++   +++     C57Bl/6 5 PMN [33]
60 minutes     - + ++ +++ ++    C57Bl/6 J 7 Lγ-6G [34]
60 minutes       +++ ++   + - Wistar 4 MPO [35]
60 minutes   - ++   ++   +++    - Wistar 6 MPO [36]
120 minutes    ++   +++   +     Wistar 8 MPO [37]
120 minutes      +++    -   - Sprague–Dawley 5 H&E [38]
120 minutesΔ   + ++   +++ +++ + -   - Wistar 4 H&E [28]
pMCAOΔ    -   + + +++ +   - Wistar 6 H&E [26]
pMCAOΔ   - -   + +++ ++ -   - Wistar 5 H&E [28]
  1. Crosses represent the following amount of cells presented as percentage of the highest cell number: +, 25 to 49%; ++, 50 to 94%; +++, 95 to 100%; -, <25%. ΔWeighted average. H&E, hematoxylin and eosin; MPO, myeloperoxidase; n, number of animals included; neutro, neutrophil granulocyte; pMCAO, permanent middle cerebral artery occlusion; PMN, polymorphonuclear; tMCAO, transient middle cerebral artery occlusion.