Leukocyte infiltration in experimental stroke

Table 5 Amount of T-cells (CD3 and CD5), T-helper cells (CD4), cytotoxic T-cells (CD8) and B-cells (B220) (normalized) at different time points post-ischemia

Occlusion time	Amount of lymphocytes (days of survival)										Marker	n	Strain	Reference
	<1	1	2	3	4	5	6	7	14	≥30
60 minutes	-	+++									CD3	6	C57Bl/6	[42]
60 minutes	-	-	+	+++	++						CD3	6	C57Bl/6	[34]
pMCAO		-				+++					CD3	8	C57Bl/6	[43]
pMCAO	+++	++		++				++			CD3	ns	CB17	[44]
pMCAO	-	+	+				+++				CD3	6	Sprague–Dawley	[45]
pMCAO		+		++				+++	++	+	CD5	5	Wistar	[41]
120 minutes	+++	++		+							CD4	8	Wistar	[37]
pMCAO	++	++		++					++		CD4	ns	CB17	[44]
120 minutes	-	-		+++							CD8	8	Wistar	[37]
pMCAO			+		++			+++	++	-	CD8	5	Wistar	[41]
60 minutes		-	-	-	+	+++					B220	6	C57Bl/6	[34]
pMCAO			-			+++					B220	8	C57Bl/6	[43]

Crosses represent the following amount of cells presented as the percentage of the highest cell number: +, 25 to 49%; ++, 50 to 94%; +++, 95 to 100%; -,<25%. n, number of animals included; ns, not shown; pMCAO, permanent middle cerebral artery occlusion.

ISSN: 1742-2094