Skip to main content

Table 5 Amount of T-cells (CD3 and CD5), T-helper cells (CD4), cytotoxic T-cells (CD8) and B-cells (B220) (normalized) at different time points post-ischemia

From: Leukocyte infiltration in experimental stroke

Occlusion time Amount of lymphocytes (days of survival) Marker n Strain Reference
  <1 1 2 3 4 5 6 7 14 ≥30     
60 minutes - +++          CD3 6 C57Bl/6 [42]
60 minutes - - + +++ ++       CD3 6 C57Bl/6 [34]
pMCAO   -     +++      CD3 8 C57Bl/6 [43]
pMCAO +++ ++   ++     ++    CD3 ns CB17 [44]
pMCAO - + +     +++     CD3 6 Sprague–Dawley [45]
pMCAO   +   ++     +++ ++ + CD5 5 Wistar [41]
120 minutes +++ ++   +        CD4 8 Wistar [37]
pMCAO ++ ++   ++      ++   CD4 ns CB17 [44]
120 minutes - -   +++        CD8 8 Wistar [37]
pMCAO    +   ++    +++ ++ - CD8 5 Wistar [41]
60 minutes   - - - + +++      B220 6 C57Bl/6 [34]
pMCAO    -    +++      B220 8 C57Bl/6 [43]
  1. Crosses represent the following amount of cells presented as the percentage of the highest cell number: +, 25 to 49%; ++, 50 to 94%; +++, 95 to 100%; -,<25%. n, number of animals included; ns, not shown; pMCAO, permanent middle cerebral artery occlusion.