Figure 4
From: Altered inflammatory responsiveness in serotonin transporter mutant rats
Analysis of chemokine ligand 1 (CX3CL1) gene expression in the hippocampus of SERT mutant rats. Basal CX3CL1 gene expression is altered in the ventral hippocampus of mutant rats (B) but not in the dorsal hippocampus (A). The data, expressed as percentage of SERT+/+ animals (set at 100%), are the mean ± SEM of at least five independent determinations. ***P < 0.001 vs. SERT+/+ (one-way ANOVA with SCPHT). The expression of CX3CL1 is modulated in dorsal (C) and ventral (D) hippocampus of WT or SERT+/− animals 1 or 5 days after an LPS challenge. The data are expressed as percentage of the respective saline-injected counterpart (set at 100%, dashed line) and represent the mean ± SEM of at least five independent determinations. #P < 0.5, ###P < 0.001 vs. control (one-way ANOVA with SCPHT).