Figure 1

T cells in lesions of spastic mice. Immunohistochemistry showing (A) CD8⁺ and (B) CD4⁺ T cells in the dorsal column of a spastic mouse. (C) to (F) Major histocompatibility complex (MHC) class I antigen staining expressed on (C) endothelial cells, and (D) microglia (E, F), but not on neurons. (G) to (I) MHC class II staining on ramified cells resembling microglia but not neurons (H, I). A to E, G to H, bar = 10 μm; F and I, bar = 5 μm.