Figure 3

Production of cytotoxic molecules in spastic mice. (A) Granzyme B-positive staining (indicated by arrows) was performed on paraffin-embedded spinal cord sections: bar = 10 μm. (B) Gel electrophoresis of PCR products show perforin expression is increased in spastic mice (hypoxanthine guanine phosphoribosyl transferase (HPRT) = internal control). NF-L, neurofilament light.