Evaluation of MHC-I expression in control and FCD I, FCD IIa, FCD IIb, TSC and GG. (A) and (B): MHC-I immunoreactivity scores (total score; see material and methods for details) in microglial cells and neurons. (C): Graph showing percentages of neuronal cells immunoreactive for NeuN and co-expressing MHC-I. Data are expressed as mean ± standard error of mean (SEM). P < 0.05 compared to FCD I and controls. FCD, focal cortical dysplasia; TSC, tuberous sclerosis complex; GG, ganglioglioma; MHC-I, major histocompatibility complex class I; ND, not determined; nd, not detectable.