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Figure 8 | Journal of Neuroinflammation

Figure 8

From: Inflammatory demyelination induces glia alterations and ganglion cell loss in the retina of an experimental autoimmune encephalomyelitis model

Figure 8

Interleukin-6 secretion in the retina. (A) Sections of CO and EAE mice were double stained with IL-6 (green) and GFAP (red). The merged image shows IL-6 positive vesicles encapsulated by macroglial (GFAP) processes in CO and EAE animals. Scale bar: 20 μm. (B) Significantly more IL-6 positive vesicles were noted in EAE retinas (8.0 ± 0.8 vesicles/retina) compared to CO (4.9 ± 0.5 vesicles/retina, P = 0.0072). **: p<0.01; CO, control; EAE, experimental autoimmune encephalomyelitis; GCL, ganglion cell layer; GFAP, glial fibrillary acidic protein; IL-6, interleukin-6.

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