Table 4 Preoperative CSF cytokine levels of patients with and without postoperative delirium
Cytokine/chemokine | Concentration (pg/mL) | P value | |
|---|---|---|---|
No delirium (N=38) | Delirium (N=23) | ||
| Â | Median (IQR) | Median (IQR) | Â |
Flt-3L | 20.16 (18.2-29.5) | 16,54 (12.2-20.2) | 0.021 |
G-CSF | 31.26 (14.7-55.8) | 23.15 (14.7-33.9) | 0.233 |
IFN-α2 | 31.70 (21.1-41.1) | 24.41 (17.7-34.1) | 0.136 |
IFN-γ | 1.61 (1.6-2.4) | 1.61 (1.6-2.4) | 0.336 |
IL-1α | 0.28 (0.2-2.3) | 0.78 (0.1-1.3) | 0.170 |
IL-1ra | 6.90 (2.9-6.9) | 2.90 (2.9-6.9) | 0.032 |
IL-6 | 0.99 (0.2-2.2) | 0.21 (0.1-0.7) | 0.005 |
IL-8 | 28.40 (22.7-42.5) | 25.25 (19.4-37.6) | 0.308 |
IL-15 | 3.47 (1.4-4.5) | 2.79 (1.4-3.5) | 0.060 |
IP-10 | 270.84 (183.1-350.6) | 334.21 (241.0-590.0) | 0.064 |
MCP-1 | 312.67 (257.2-422.6) | 301.79 (241.6-389.5) | 0.634 |
MCP-3 | 19.4 (12.2-25.2) | 19.4 (19.4-25.2) | 0.375 |
PDGF-AA | 8.04 (5.6-10.3) | 6.67 (5.4-9.0) | 0.267 |
RANTES | 3.50 (0.1-3.5) | 0.08 (0.1-3.5) | 0.290 |
sCD40-L | 1.14 (0.06-1.1) | 0.06 (0.06-1.1) | 0.263 |
TGF-α | 1.99 (1.4-3.2) | 1.99 (1.4-2.6) | 0.411 |