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Figure 6 | Journal of Neuroinflammation

Figure 6

From: The plasminogen activator system: involvement in central nervous system inflammation and a potential site for therapeutic intervention

Figure 6

A dministration of the plasminogen activator inhibitor-derived peptide PAI-1dp ameliorated the clinical course of experimental autoimmune encephalomyelitis (EAE). EAE was induced in wild-tupe (WT) mice by immunization with myelin oligodendrocyte glycoprotein (MOG)35–55. The animals were given either placebo or PAI-dp 0.5 mg/kg twice daily by intraperitoneal injection. Results are expressed as the mean clinical score ± standard error (SE) of three separate experiments. (n = 16 for each group). The results are the mean of three separate experiments.

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Journal of Neuroinflammation

ISSN: 1742-2094