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Figure 5 | Journal of Neuroinflammation

Figure 5

From: TSG (2,3,4’ ,5-tetrahydroxystilbene 2-O-β-D-glucoside) suppresses induction of pro-inflammatory factors by attenuating the binding activity of nuclear factor-κB in microglia

Figure 5

Effects of TSG on lipopolysaccharide (LPS)-initiated inhibitor of κB α (IκB-α) degradation and nuclear factor κB (NF-κB) phosphorylation in BV-2 cells. (A) LPS-induced IκB-α degradation was not altered in TSG (50 μM, 30 minutes)-incubated BV-2 cells. (B) Quantitative analysis of the effect of TSG on IκB-α degradation in LPS-treated cells (n = 3, *P < 0.05 versus control). (C) LPS-induced NF-κB phosphorylation was also not changed by TSG treatment (50 μM, 30 minutes). (D) Quantitative analysis of the effect of TSG on NF-κB phosphorylation level in LPS-treated cells (n = 3, *P < 0.05 versus control). All data were shown as mean ± standard error. GAPDH, glyceraldehyde-3-phosphate dehydrogenase.

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Journal of Neuroinflammation

ISSN: 1742-2094