Overview of regions of interest in the right hemisphere at the posterior hippocampus/mid-thalamus level. (A) Regions of interest for the detection of IBA-1 immunoreactivity, 1 = hippocampus, 2 = subcortical white matter and 3 = periventricular white matter; (B) regions of interest for the detection of O4-positive cell density, 1 = medial periventricular white matter, 2 = intermediate periventricular white matter, 3 = lateral periventricular white matter, and 4 = subcortical white matter. Scale bar = 4 mm. The white dashed box (5) indicates in which region the myelin binding protein (MBP) images in Figure
7 were obtained.