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Figure 8 | Journal of Neuroinflammation

Figure 8

From: The absence of myelin basic protein promotes neuroinflammation and reduces amyloid β-protein accumulation in Tg-5xFAD mice

Figure 8

Elevated MMP-9 levels in Tg-5xFAD/MBP -/- mice. (A) Gelatin zymography of brain homogenates shows increased levels of MMP-9, but not MMP-2, in bigenic Tg-5xFAD/MBP-/- mice. (B) Quantification of gelatin zymography signals show MMP-9, but not MMP-2, was increased 2-fold in bigenic Tg-5xFAD-MBP-/- mice. Data presented are mean ± SEM of four mice per group. *p < 0.05. (C) Immunoblot of MMP-9 in brain homogenates of Tg-5xFAD mice and bigenic Tg-5xFAD/MBP-/- mice.

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Journal of Neuroinflammation

ISSN: 1742-2094