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Figure 5 | Journal of Neuroinflammation

Figure 5

From: Optical tomographic imaging of near infrared imaging agents quantifies disease severity and immunomodulation of experimental autoimmune encephalomyelitis in vivo

Figure 5

Clinical scores and disease incidence for control and PLP-tolerized mice

Clinical scores and disease incidence for control and PLP-tolerized mice. Mice were injected with OVA322-339-conjugated or PLP139-151-conjugated PLGA nanoparticles 7 days prior to immunization with PLP139-151 in CFA (as described in Materials and Methods). Mean clinical scores (left panel) were assessed on days 7 through 15 following immunization, and disease incidence (right panel) was determined based on mice with a score of at least 1.

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