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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Activation of the inflammatory transcription factor nuclear factor interleukin-6 during inflammatory and psychological stress in the brain

Figure 2

Novel environment stress (stress) induced a significant increase in nuclear NF-IL6-IR in the pituitary of rats. (A, B) Some nuclear (DAPI, blue) NF-IL6-IR (red) can be observed in unstimulated control animals. (C-F) After novel environment-stress was introduced, nuclear NF-IL6-IR peaked (D, E) 60 to 90 min later and (G) declined to control levels at 240 min. GFAP detection (green) was used to better visualize the posterior pituitary lobe. (H) The schematic overview clearly depicts the substructure of microphotographs, containing all pituitary lobes (anterior lobe (AL), intermediate lobe (IL), and posterior lobe (PL)). Brightness, contrast, and color balance were adjusted for better representation of the actual data. The scale bar in A represents 100 μm (applies to A-G).

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