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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Minocycline prevents retinal inflammation and vascular permeability following ischemia-reperfusion injury

Figure 3

Leukostasis and retinal tissue invasion of CD45-positive leukocytes following ischemia-reperfusion (IR). Eyes were subjected to IR for 45 min or needle puncture only (Sham) and after 48 h of reperfusion retinas were removed, stained with antibodies to CD45 (magenta), isolectin B4 (IB4, green) and Hoechst nuclear stain (blue) and then flat mounted. Representative images showing CD45-staining leukocytes within IB4-stained vessels from IR retina (A) and sham retina (B) are shown along with magnified images (C and D) of CD45-positive cells (arrows) found within retinal tissue from IR retinas.

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