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Figure 8 | Journal of Neuroinflammation

Figure 8

From: Immunomodulation targeting of both Aβ and tau pathological conformers ameliorates Alzheimer’s disease pathology in TgSwDI and 3xTg mouse models

Figure 8

Levels of soluble Aβ40 and Aβ42 in 20% brain homogenates. (A) TgSwDI treated and Tg control groups show a 31% and 34% reduction in the levels of Aβ40 (*P = 0.02) and Aβ42 (*P = 0.01). (B) There was a 55% and 84% reduction in the levels of Aβ40 (***P < 0.0001) and Aβ42 (***P = 0.0004) between 3xTg treated and vehicle control groups, respectively. P values are by unpaired two-tailed t-tests. Tg, transgenic.

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