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Figure 9 | Journal of Neuroinflammation

Figure 9

From: Immunomodulation targeting of both Aβ and tau pathological conformers ameliorates Alzheimer’s disease pathology in TgSwDI and 3xTg mouse models

Figure 9

Quantitation of Aβ oligomers. Oligomer levels in the soluble brain fractions were determined using an ELISA specific to aggregated/oligomeric Aβ. Two-tail unpaired t-tests of this ELISA data show a significant reduction of levels of Aβ aggregates/oligomers for the pBri-treated group vs. the vehicle group for both (A) TgSwDI mice (35% reduction) and (B) 3xTg mice (37% reduction) (*P = 0.02 and *P = 0.04, respectively, by unpaired two-tailed t-tests). Tg, transgenic.

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Journal of Neuroinflammation

ISSN: 1742-2094