Figure 4

Microglia were NOX4 ⁺ ipsilateral to the injury site. Cells labeled with the microglial marker CD11b (green) were not NOX4 (red) positive in naïve animals. By 24 hours and 7 days post-injury, some cells positive for CD11b were also positive for NOX4 (arrows). By 7 days post-injury, all CD11b⁺ cells in the injury site were positive for NOX4. At 28 days, not all of the CD11b⁺ cells were NOX4⁺. Bar = 50 μm.