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Figure 5 | Journal of Neuroinflammation

Figure 5

From: Tamoxifen as an effective neuroprotectant against early brain injury and learning deficits induced by subarachnoid hemorrhage: possible involvement of inflammatory signaling

Figure 5

NF-κB activity in the brain area surrounding the blood clot in control group (n = 6), subarachnoid hemorrhage (SAH) group (n = 6), SAH + vehicle group (n = 6), and SAH + tamoxifen group (n = 6). Upper, electrophoretic mobility shift assay (EMSA) autoradiography of NF-κB DNA binding activity. Lane 1, control; lane 2, SAH; lane 3, SAH + vehicle; lane 4, SAH + tamoxifen, respectively. Bottom, Levels of NF-κB DNA binding activity quantified by computer-assisted densitometric scanning and expressed as arbitrary densitometric units (ADU). **P <0.01 between control animals versus SAH animals; #P <0.05 between SAH + vehicle animals versus SAH + tamoxifen animals; n.s. P >0.05 between SAH animals versus SAH + vehicle animals.

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Journal of Neuroinflammation

ISSN: 1742-2094