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Figure 6 | Journal of Neuroinflammation

Figure 6

From: Tamoxifen as an effective neuroprotectant against early brain injury and learning deficits induced by subarachnoid hemorrhage: possible involvement of inflammatory signaling

Figure 6

Changes of inflammatory mediators in the injured brains as determined by ELISA in control group (n = 6), subarachnoid hemorrhage (SAH) group (n = 6), SAH + vehicle group (n = 6), and SAH + tamoxifen group (n = 6). SAH could induce the significantly increased concentrations of IL-1β, TNF-α and IL-6 in the rat brain after SAH. In SAH + tamoxifen group, the cortical concentrations of IL-1β, TNF-α, and IL-6 were markedly downregulated following SAH. *P <0.05 and **P <0.01 between control animals versus SAH animals; #P <0.05 and ##P <0.01 between SAH + vehicle animals versus SAH + tamoxifen animals; n.s. P >0.05 between SAH animals versus SAH + vehicle animals.

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Journal of Neuroinflammation

ISSN: 1742-2094