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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Anti-inflammatory and anti-amyloidogenic effects of a small molecule, 2,4-bis(p-hydroxyphenyl)-2-butenal in Tg2576 Alzheimer’s disease mice model

Figure 2

Effect of HPB242 on improvement of memory impairment in Tg2576 mice. The training trial was performed three times a day for 7 days. Swimming time (A) and swimming distance (B) to the platform were automatically recorded. Two days after the training trials, a probe test was performed. The time spent in the target quadrant and target site crossing within 60 s was represented (C). Each value is presented as mean ± standard error of the mean (SEM) from eight mice. To perform the passive avoidance test, mice were given an electric shock on entering the dark compartment for training on the learning day. After 2 days, the retention time in the illuminated compartment was recorded (D). Each value is presented as mean ± SEM from eight mice. #Significantly different to non-Tg mice (P < 0.05), *Significantly different to non-treated Tg2576 mice (P < 0.05).

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