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Figure 5 | Journal of Neuroinflammation

Figure 5

From: Cerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery

Figure 5

Cerebral ischemia leads to an immediate activation of neutrophils and monocytes. (a) After cerebral ischemia (i.e., DHCA), CD62L expression is the same in arterial and venous blood, but CD11b expression is higher in the venous sample compared to arterial (P <0.01). (b) After continuous cerebral perfusion (i.e., ACP), neutrophil CD11b and CD62L expressions remain stable. (c) After cerebral ischemia (DHCA), in the venous sample, the proportion of monocytes that is CD16- is decreased compared to arterial, due to an increase in CD16intermediate and CD16+ monocyte subpopulations (all P <0.01). (d) After continuous cerebral perfusion (ACP), the monocyte subpopulations remain unchanged.

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