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Table 3 Inflammatory results for later time points

From: Cerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery

Neutrophils and monocytes

DHCA

ACP

P

30 min reperfusion

   

 Monocyte count

0.13 (0.06-0.23)

0.12 (0.07-0.14)

0.76

  % CD16- monocytes

68 (60–85)

74 (50–88)

0.84

  % CD16int monocytes

7.4 (5.7-14)

6.1 (2.4-10)

0.36

  % CD16+ monocytes

19 (9.2-33)

16 (6.0-43)

0.76

 Neutrophil count

1.5 (1.2-1.9)

1.1 (0.7-1.7)

0.24

  Neutrophil CD62L expression

193 (67–227)

187 (134–307)

0.44

  Neutrophil CD11b expression

610 (469–816)

672 (508–926)

0.85

4 h postoperative

   

 Monocyte count

3.1 (1.7-4.8)

2.0 (1.5-2.4)

0.15

  % CD16- monocytes

86 (85–95)

87 (78–94)

0.74

  % CD16int monocytes

6.8 (4.9-8.7)

7.5 (3.2-11)

0.72

  % CD16+ monocytes

6.0 (1.7-8.5)

4.5 (2.4-9.9)

0.88

 Neutrophil count

8.2 (6.0-10.2)

6.9 (4.8-8.5)

0.43

  Neutrophil CD62L expression

281 (253–300)

292 (257–356)

0.43

  Neutrophil CD11b expression

478 (276–621)

462 (237–594)

0.65

24 h postoperative

   

 Monocyte count

1.4 (1.0-2.2)

0.9 (0.7-1.3)

0.29

  % CD16- monocytes

88 (78–94)

81 (73–91)

0.23

  % CD16int monocytes

10 (6.0-21)

10 (6.0-26)

0.61

  % CD16+ monocytes

2.9 (1.7-3.0)

6.0 (3.0-7.0)

0.01

 Neutrophil count

11 (9.0-16)

8.8 (7.0-15)

0.32

  Neutrophil CD62L expression

260 (196–322)

300 (227–336)

0.35

  Neutrophil CD11b expression

359 (227–491)

288 (176–368)

0.22

Cytokines and chemokines

   

4 h postoperative

   

 IL-1β

0.25 (0.25-0.25)

0.25 (0.25-4.2)

0.61

 IL-6

91 (48–114)

49 (41–65)

0.14

 IL-8

77 (59–109)

53 (29–64)

0.04

 IL-10

2760 (2474–7077)

3112 (768–5758)

0.42

24 h postoperative

   

 IL-1β

0.25 (0.00-3.9)

2.2 (0.51-3.5)

0.48

 IL-6

19 (11–34)

23 (7.6-33)

0.76

 IL-8

44 (27–67)

15 (11–37)

0.05

 IL-10

24 (16–33)

15 (7.4-31)

0.20

  1. Values represent medians (interquartile ranges). Neutrophil and monocyte counts in 109/L, neutrophil expressions in median fluorescence intensity (MFI), cytokine and chemokine concentrations in pg/ml. ACP, antegrade cerebral perfusion; DHCA, deep hypothermic circulatory arrest.