TLR4 knockout results in faster hematoma resolution. (A) Representative brain sections from WT and TLR4-knockout mice at 1, 3, and 5 days after intrastriatal injection of blood. (B) Compared with WT mice, TLR4-knockout mice had significantly smaller hemotomas at 3 and 5 days after ICH. Hematoma volume was measured on coronal slices (2 mm thick) using image analysis software. Scale bar: 1 mm. **P < 0.05 versus WT mice.