Skip to main content

Advertisement

Table 1 Effects of RA on the viability and LDH leakage in SH-SY5Y cells exposed to oxygen-glucose deprivation

From: Rosmarinic acid protects against experimental diabetes with cerebral ischemia: relation to inflammation response

Groups OGD Content (μM) Cell viability (%) LDH leakage (%)
Normal _ 100.0 ± 4.7 4.1 ± 1.2
Control + 52.0 ± 6.8# 24.7 ± 4.2#
RA + 1 59.2 ± 7.3 21.9 ± 2.8
+ 3 64.2 ± 5.8* 19.6 ± 3.5*
+ 9 69.0 ± 9.1** 16.5 ± 2.1**
+ 27 72.8 ± 7.4** 14.0 ± 3.1**
+ 81 73.5 ± 8.3** 13.3 ± 1.7**
  1. After 3 h oxygen-glucose deprivation (OGD) followed by 12 h incubation with RA, cell viability and LDH leakage were assessed. RA indicated Rosmarinic acid. OGD, oxygen-glucose deprivation. Values are mean ± S.D. (n = 6). Significance was determined by one-way ANOVA followed by Dunnett's test. # P <0.01 versus normal group; * P <0.05, ** P <0.01 versus Control group.