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Table 5 Effect of RA on cerebral Evans blue extravasation and MPO activity in ischemia-reperfused rats

From: Rosmarinic acid protects against experimental diabetes with cerebral ischemia: relation to inflammation response

Group Dose (mg/kg) Evans blue extravasation (μg/g wet weight) MPO activity (U/g wet weight)
Control 0.59 ± 0.13 0.02 ± 0.01
Diabetic 0.67 ± 0.18 0.03 ± 0.01
Vehicle 3.93 ± 0.62# 0.18 ± 0.04#
RA 50 1.73 ± 0.42* 0.09 ± 0.02*
  1. Data are means ± SD, with n = 5 for each group. # P <0.01 vs. diabetic animals; * P <0.01 vs vehicle-treated animals. Significance was determined by one-way ANOVA followed by Dunnett's test.