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Table 5 Effect of RA on cerebral Evans blue extravasation and MPO activity in ischemia-reperfused rats

From: Rosmarinic acid protects against experimental diabetes with cerebral ischemia: relation to inflammation response

Group

Dose (mg/kg)

Evans blue extravasation (μg/g wet weight)

MPO activity (U/g wet weight)

Control

—

0.59 ± 0.13

0.02 ± 0.01

Diabetic

—

0.67 ± 0.18

0.03 ± 0.01

Vehicle

—

3.93 ± 0.62#

0.18 ± 0.04#

RA

50

1.73 ± 0.42*

0.09 ± 0.02*

  1. Data are means ± SD, with n = 5 for each group. # P <0.01 vs. diabetic animals; * P <0.01 vs vehicle-treated animals. Significance was determined by one-way ANOVA followed by Dunnett's test.
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Journal of Neuroinflammation

ISSN: 1742-2094