Figure 1
From: An autoinflammatory neurological disease due to interleukin 6 hypersecretion
Neuroradiological findings in different examinations. Last magnetic resonance imaging (MRI) study (A and B, axial T2-weighted images; C, apparent diffusion coefficient (ADC) map) shows diffuse hyperintensities in the white matter, patchy involvement of the basal ganglia and thalami, and arachnoid cysts (arrows). ADC is increased, consistent with increased water content in the brain tissue. Comparison of MRI studies obtained 4 years apart (D, E, coronal T2-weighted images) shows progression of the leukoencephalopathy, decrease in size of the subarachnoid spaces along the convexity, and slight enlargement of the ventricles. Recent computed tomography (CT) scan (F) demonstrates tiny subcortical calcifications (arrows). See Additional file 1 for further details.