Figure 3

Protracted anti-inflammatory drug treatment reduced the frequency of spontaneous recurrent seizures (SRS) among epileptic animals. Bar graphs represent the average number of seizures observed. Over 3 weeks of continuous video and EEG monitoring, vehicle-treated animals (VEHS) presented an average of 2.9 ± 0.6 seizures per week, while those treated with a single injection of anti-inflammatory drug (AID) did not show significant reduction in seizure frequency and exhibited an average of 2.5 ± 0.4 seizures per week (P >0.5). Animals treated with daily injections of AID for 10 consecutive days showed a marked decrease in SRS frequency (*P <0.05 10 days of drug treatment vs. two other groups, n = 8).