Figure 6
From: Amelioration of autoimmune neuroinflammation by the fusion molecule Fn14·TRAIL
Effect of Fn14·TRAIL in vitro on Jurkat cells. Jurkat cells were exposed to two concentrations of Fn14·TRAIL for 24 and 48 h, as well as to a/FAS as positive control. Apoptosis was measured using an Annexin-PI kit, as described in Materials and Methods. The extent of apoptosis induced by Fn14·TRAIL after 24 and 48 h was 2.5 and 3.5 fold, respectively in the presence of 300 ng/ml Fn14·TRAIL.