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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Corticosteroid therapy in a patient with cerebral amyloid angiopathy-related inflammation

Figure 2

Neuropathological findings of the biopsy specimen from the right parietal lobe of the patient with CAA-ri. (A) Multifocal lymphocytic infiltrates around the leptomeningeal-parenchymal blood vessels, with hyaline thickening and splitting of the walls (double-barrel formation) (hematoxylin-eosin); (B) The perivascular lymphocytic infiltrates consisting primarily of UCHL1 + T cells (serial section of [A]; UCHL1 immunostain); (C) An affected blood vessel, showing perivascular multinucleated giant cells (arrows) (hematoxylin-eosin); (D) Dense deposition of Aβ protein in the affected blood vessel wall (serial section of [C]; Aβ immunostain).

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