Figure 10

CD11b expression is not altered in contralateral or ipsilateral regions after ischemic stroke and 24 h of reperfusion. A Representative confocal maximum intensity projection images of CD11b expression in ipsilateral and contralateral brain regions (1 striatum; 2–4 cortex) after 60 min of focal ischemia and 24 h of reperfusion. B Enlarged image of microglia (top panel, iba-1) and corresponding CD11b expression (bottom panel) from boxed region as depicted in (A). C There were no significant changes in microglia CD11b between any experimental groups (sham, contralateral and ipsilateral) at any region after ischemic stroke and 24 h of reperfusion. Data were tested for statistical differences between ipsilateral vs. contralateral regions using one-way ANOVA analysis (n = 5 contralateral/ipsilateral, n = 6 sham, *p < 0.05). All data are mean ± SEM. Scale bar = 10 μm.