Figure 4
Post-injury hemorrhages and apoptosis. (A) Overview of the injured brain at bregma level −1.5 mm (see Figure 1C) at one day after cFPI, a model of TAI in mice. The injury produces small hemorrhages in the cortex underlying the impact; (B) Overview of the TUNEL staining distribution at one day post-injury; (C) Immunohistochemical image shows apoptotic cells in the cortex and dentate gyrus of the hippocampus although not in sham-injured controls. PID: Post-injury day.