Figure 2
From: Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1 −/− mice
Schematic of systemic lipopolysaccharide administration regimens and measurable outcomes. Wild-type and DJ-1−/− mice were given low-dose lipopolysaccharide or an equivalent volume of saline vehicle twice a week intraperitoneally (i.p.) for the indicated times. Locomotor behavior was evaluated before and during the course of treatment. Groups of mice were sacrificed as indicated for biochemical and immunohistological analyses. IHC, immunohistochemistry; mo, months; QPCR, quantitative polymerase chain reaction; HPLC, high-performance liquid chromatography.