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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Different actions of endothelin-1 on chemokine production in rat cultured astrocytes: reduction of CX3CL1/fractalkine and an increase in CCL2/MCP-1 and CXCL1/CINC-1

Figure 2

Effects of Ala 1,3,11,15 -ET-1 on CCL2, CXCL1 and CX3CL1 mRNA expression in cultured rat astrocytes. Serum-starved astrocytes were treated with 100 nM Ala1,3,11,15-ET-1 for the times indicated. The expression of CCL2, CXCL1 and CX3CL1 mRNA was normalized to G3PDH and expressed as the % of 0 hour. Data are expressed as the mean ± SEM of 4 to 14 experiments. *P <0.05 versus 0 hour by one-way ANOVA followed by Dunnett’s test. ANOVA, analysis of variance; ET-1, endothelin-1; G3PDH, glyceraldehyde-3-phosphate dehydrogenase; SEM, standard error of the mean.

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