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Table 2 Sickness response measures following IP LPS

From: Interleukin-1 beta converting enzyme is necessary for development of depression-like behavior following intracerebroventricular administration of lipopolysaccharide to mice

  Δ Body weight (g / 24 h) Line crossings (# / 5 min) Rearings (# / 5 min)
WT −0.02 ± 0.11a 60.3 ± 5.6a 42.9 ± 5.0a
WT-LPS −2.84 ± 0.09b 36.8 ± 6.5b 26.9 ± 3.0b
ICE KO −0.09 ± 0.10a 35.6 ± 3.8b 27.0 ± 3.0b
ICE KO-LPS −2.82 ± 0.12b 36.9 ± 2.6b 25.2 ± 2.4b
  1. Body weight was measured at 0 and 24 h and body weight change was calculated from these measures; locomotor activity was tested 24 h after treatment. Averages within columns with different superscript letters are significantly different; P <0.05.