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Table 2 Sickness response measures following IP LPS

From: Interleukin-1 beta converting enzyme is necessary for development of depression-like behavior following intracerebroventricular administration of lipopolysaccharide to mice

 

Δ Body weight (g / 24 h)

Line crossings (# / 5 min)

Rearings (# / 5 min)

WT

−0.02 ± 0.11a

60.3 ± 5.6a

42.9 ± 5.0a

WT-LPS

−2.84 ± 0.09b

36.8 ± 6.5b

26.9 ± 3.0b

ICE KO

−0.09 ± 0.10a

35.6 ± 3.8b

27.0 ± 3.0b

ICE KO-LPS

−2.82 ± 0.12b

36.9 ± 2.6b

25.2 ± 2.4b

  1. Body weight was measured at 0 and 24 h and body weight change was calculated from these measures; locomotor activity was tested 24 h after treatment. Averages within columns with different superscript letters are significantly different; P <0.05.