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Figure 3 | Journal of Neuroinflammation

Figure 3

From: Absence of IL-1β positively affects neurological outcome, lesion development and axonal plasticity after spinal cord injury

Figure 3

Systemic application of recombinant IL-1β impairs neurological outcome after spinal cord compression injury. Locomotion analysis using the Basso Mouse Scale (BMS) showed a significant early worsening of neurological outcome after spinal cord compression injury (SCI) and systemic administration of recombinant IL-1β (rIL-1β) compared with control mice. At days 1 and 2 after SCI, the rIL-1β-treated mice scored more than 2 points of the BMS lower than the control mice, but the significant difference was progressively lost and they scored in the same range of values as control mice at day 7 after lesion. *P <0.05, two-way analysis of variance.

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Journal of Neuroinflammation

ISSN: 1742-2094