Table 1 Subject characteristics
From: Cerebrospinal fluid neopterin decay characteristics after initiation of antiretroviral therapy
Characteristic | non-HAD (n = 102) | HAD (n = 7) | P-value* |
|---|---|---|---|
Sex (male), number (%) | 101 (99) | 6 (86) | 0.0125 |
Age, years | 41 (18, 68) | 46 (30, 58) | 0.184 |
CD4 cell count (×106 cells/L) | 190 (0, 630) | 138 (53, 344) | 0.711 |
CPE score | 8.0 (5.0, 13.0) | 9.0 (6.0, 13.0) | 0.060 |
CSF neopterin (nmol/L) | 19.6 (4.0, 138.0) | 54.4 (13.7, 154.0) | 0.001 |
Blood neopterin (nmol/L) | 21.7 (6.8, 77.0) | 25.0 (12.0, 28.9) | 0.359 |
CSF HIV RNA (log10 copies/mL) | 3.93 (1.28, 6.26) | 5.08 (3.08, 5.98) | 0.015 |
Plasma HIV RNA (log10 copies/mL) | 5.05 (1.28, 6.89) | 5.31 (4.68, 5.61) | 0.277 |
Follow-up, weeks | 84.7 (0.4, 682.7) | 21.6 (4.1, 150.0) | 0.017 |