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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Innate immunity in the Grid2Lc/+ mouse model of cerebellar neurodegeneration: glial CD95/CD95L plays a non-apoptotic role in persistent neuron loss-associated inflammatory reactions in the cerebellum

Figure 1

Microglial activation in the Grid2 Lc/+ cerebellum. Sagittal sections of wild-type (A,C) and Grid2Lc/+ (B,D) cerebella from 21-day-old (A,B) and adult (C,D) mice were stained by the dinucleoside diphosphatase technique. Microglia (arrow) and blood vessels (arrow-head) are labeled. (B and D) Isolated activated microglial cells with enlarged cell bodies and thick processes are present specifically in the cerebellum of 21-day-old Grid2Lc/+mice (B). In adult (D) mice, microglia are mostly organized into clusters (open arrow). Scale bars: A and B, 30 ÎĽm; C and D, 100 ÎĽm.

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