Time | 0 week | 4 weeks |
---|
CTL | 6.26 ± 1.04 | 6.45 ± 0.92 |
DPN | 19.58 ± 3.37a
| 20.78 ± 4.10 |
DPN + T1 | 20.95 ± 3.86a
| 20.58 ± 3.71 |
DPN + T2 | 19.95 ± 3.66a
| 20.53 ± 6.11 |
- Note: Animals were injected subcutaneously with rhTNFR:Fc in rhTNFR:Fc-treated groups or with physiological buffered saline (PBS) as a vehicle in normal control (CTL) and in DPN groups twice per week for 4 weeks. Unit of blood glucose: mmol/L. DPN, diabetic peripheral neuropathy; T1, 0.4 mg/kg rhTNFR:Fc treatment; T2, 4 mg/kg rhTNFR:Fc treatment.
-
aCompared with group of CTL, P <0.05 (n = 12).