Figure 3
From: Impaired toll-like receptor 8 signaling in multiple sclerosis
TLR 8 and 3 gene expression in PBMC. Patients with MS and healthy donors differ in baseline (A) TLR8 transcript expression (Student’s unpaired two-tailed t-test, ** = P <0.005, n = 10 per group) but not in (B) TLR3 transcript expression (n = 7 per group). Data shown are median ± 25% to 75% interquartile range relative TLR mRNA quantification at baseline for each individual normalized to GAPDH and a reference sample. MS, multiple sclerosis; PBMC, peripheral blood mononuclear cells; TLR, Toll-like receptor.