Figure 6

Expression of extracellular matrix (ECM)-degrading enzymes. Gene expression was monitored by quantitative reverse transcriptase (RT)-PCR and normalized to the housekeeping gene, Hprt1. (Note the different Y-axis scales.) The values are expressed as mean ± SEM, with the number of individual cultures indicated on each bar. The genes are: Mmp2, Mmp9, Mmp12, Mmp14, Timp1, heparanase, Cat B, Cat L1, Cat S, Cat K. One-way ANOVA with Tukey’s post-hoc test revealed differences from control microglia: *P <0.05, **P <0.01, ***P <0.001.